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As of 5PM today, the Commonwealth of Massachusetts is reporting 8 newly reported confirmed deaths (8 more than yesterday) for a total of 17,584 deaths, 44 newly reported confirmed cases (11 more than yesterday - up 33.3%) for a total of 662,855 cases, and 13,113 newly reported molecular tests (11,867 less than yesterday - down 47.5%). The seven day average positivity rate is 0.42%, compared to 0.42% yesterday. Excluding higher education, the seven day average positivity rate is 0.57%, compared to 0.58% yesterday. The number of estimated active cases was 2,636 (59 less than yesterday - down 2.2%). The state also reported zero newly reported probable deaths (same as yesterday) for a total of 363 and 14 newly reported probable cases (8 more than yesterday - up 133.3%) for a total of 46,078. Combining the confirmed and probable numbers gives 8 new deaths for a total of 17,947 and 58 new cases for a total of 708,933. There were 138 COVID-19 patients in hospital (5 more than yesterday - up 3.8%), 43 COVID-19 patients in ICUs (5 less than yesterday - down 10.4%) and 23 COVID-19 patients on ventilators (intubated) (4 less than yesterday - down 14.8%).

Of the four overview trends (formerly the Page 2 "key metrics"), the 7-day average of newly confirmed cases is 85.0 (1 more than yesterday - up 1.2%), 0% above the lowest observed value of 85.0 on 6/13/2021 and 99.0% below the highest observed value of 6,238.0 on 1/8/2021. The 7-day weighted average of positive molecular test rate is 0.42% (0 less than yesterday - down 0.6%), 0% above the lowest observed value of 0.4% on 6/13/2021 and 98% below the highest observed value of 27.7% on 4/15/2020. The 7-day average number of COVID-19 patients in hospital is 157.0 (5 less than yesterday - down 3.1%), 1% above the lowest observed value of 155.0 on 8/26/2020 and 96% below the highest observed value of 3,874.0 on 4/27/2020. The 7-day average number of COVID-19 deaths is 4.0 (same as yesterday), 0% above the lowest observed value of 4.0 on 6/11/2021 and 98% below the highest observed value of 175.0 on 4/24/2020.

Statewide, hospitals reported 9,051 non-ICU beds, of which 7,436 (82.2%) were occupied by non-COVID patients, 95 (1.0%) were occupied by COVID patients, and 1,520 (16.8%) remained available. Hospitals also reported 1,346 ICU beds, of which 914 (67.9%) were occupied by non-COVID patients, 43 (3.2%) were occupied by COVID patients, and 389 (28.9%) remained available. By comparison, hospitals reported yesterday a total of 9,091 non-ICU beds, of which 7,610 (83.7%) were occupied by non-COVID patients, 85 (1%) were occupied by COVID patients, and 1,396 (15.4%) remained available. Hospitals also reported yesterday a total of 1,352 ICU beds, of which 928 (68.6%) were occupied by non-COVID patients, 48 (3.6%) were occupied by COVID patients, and 376 (27.8%) remained available.

Two weeks ago, there was no daily dashboard report, due to the Memorial Day holiday. Two weeks and one day ago, the 7 day confirmed case average was 171.0, the 7 day confirmed deaths average was 5.0, the 7 day hospitalization average was 249.0, and the 7 day weighted average positivity rate was 0.66% (or 1.00% excluding higher education).

The daily raw data file used to create this report is available here.

Compared to yesterday, today's numbers aren't so great; compared to, say, last March, they're fantastic. Deaths and cases are both up day-over-day, as are the hospitalization counts, but the estimated active case count continues to drop. The seven-day averages for cases, deaths and percent-positive continue to be at their Lowest Observed Values, while the seven-day hospitalization average continues to trend downward.

And there's another highly effective COVID-19 vaccine coming out of Phase III trials, as Novavax reported their candidate was highly effective:
Novavax's Covid-19 vaccine was highly effective in preventing symptomatic infections, hospitalizations, and severe illnesses, long-awaited results from the company's Phase 3 trial, released Monday, revealed. The vaccine was 90% protective against laboratory-confirmed symptomatic infection.

The trial results put this vaccine in the same efficacy ballpark as the mRNA vaccines produced by Pfizer-BioNTech and Moderna. But where those companies are currently producing and selling hundreds of millions of doses and are in the process of seeking full licensure from the Food and Drug Administration, Novavax still has steps it must take before it can apply for the regulatory authorizations it will need to start rolling out its vaccine.

The results were released in a statement; Novavax said it will submit the full trial data for publication in a peer-reviewed journal at a later date.

It also said it will file with several drug regulators, including the FDA, in the third quarter and expects to be able to produce 100 million doses a month by the end of that quarter, upping production to 150 million per month by the end of the year.

[ ... ]

There have been high hopes for this vaccine, which can be stored at fridge temperature, making its distribution easier than that of the mRNA vaccines. The vaccine is given in two doses, three weeks apart.

The vaccine is a so-called recombinant protein vaccine, with the spike protein of the SARS-CoV-2 virus grown in moth cells. Those proteins are formed into nanoparticles, which are then mixed with an adjuvant, a compound that boosts the immune response to the vaccine.

Not directly a big deal for the US, but likely to be huge for less-wealthy nations who've been left out so far.

The town of Acton's current Google Data Studio dashboard is showing zero active and 981 cumulative cases as of June 13. There have been no new cases shown on this dashboard since June 2. The most recent "newsflash style update" at 11:45AM on May 28, 2021 reported 978 cumulative cases with 3 individuals in isolation, 943 persons recovered and 32 fatalities.

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Edmund Schweppe

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